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What’s a playwright to do when mere family dysfunction is no longer enough to carry a script? If you’re David Lindsay-Abaire, you toss a rare disease into the mix. The title character in this 2003 comedy is a 16-year-old rapidly aging because she has progeria, living in a family whose nonstop acrimonious screeching makes them sound like howler monkeys. Shade Murray’s actors, particularly Roslyn Alexander as Kimberly and Steve Haggard as her nerdy schoolmate (a relationship with echoes of Harold and Maude), bring plenty of energy to the show. But two hours of self-absorbed diatribes punctuated by occasional Hallmark moments of tenderness start to feel long-winded even if, unlike Kimberly, you’re not counting minutes as hours. Through 12/18: Thu-Sat 8 PM, Sun 7 PM. No show Thu 11/24. A Red Orchid Theatre, 1531 N. Wells, 312-943-8722. $14-$20.