A slight sense of deja vu hangs over this offbeat comedy: like the 2007 sleeper Little Miss Sunshine (from the same producers), it takes place in a cockeyed, can-do version of the American southwest, features Alan Arkin as a cantankerous old fart, and combines morbid humor with cheery emotionalism. Taken on its own terms, though, it’s a solid indie effort with plenty of nice character strokes by screenwriter Megan Holley and razor-sharp performances by Amy Adams and Emily Blunt. They play sisters who, sick of their menial jobs, launch a business cleaning up gory crime scenes; Arkin is their father, who’s attracted to stupid get-rich-quick schemes, and there are fine supporting turns by Steve Zahn as a cop who’s cheating on his wife with Adams, Mary Lynn Rajskub as a suicide victim’s daughter befriended by Blunt, and Clifton Collins Jr. (Perry White in Capote) as the shy, one-armed shopkeeper who advises the sisters on such matters as how to dispose of brain fragments. Christine Jeffs directed. R, 102 min.