This adaptation of the John Le Carre best seller by Jeffrey Caine plays like Graham Greene redux. Ralph Fiennes stars as a mild-mannered member of the British High Commission in Kenya whose radical activist wife (Rachel Weisz) is brutally slain; investigating her murder, he gradually pieces together a tale of corruption involving the pharmaceutical industry that’s every bit as horrific as (and much more timely than) Harry Lime’s killing of babies with diluted penicillin in The Third Man. Fernando Meirelles, codirector of City of God, stresses old-fashioned storytelling and takes full advantage of his cast, including Danny Huston. R, 129 min.